There is far more information concerning Parkinson's Disease in the "Comprehensive Guide" than any other book concerning Parkinson's Disease. It details all of the causes (toxic, genetic, biochemical, pharmacological, medical) to an extent never seen before. It has a full assessment of all the treatments, established and in development, from pharmacological to natural to exercise to surgical. Every single symptom of every system in the body is detailed and fully explained well beyond what exists elsewhere. For the first time it has the complete biochemistry and biology. Besides that is has all the methods of diagnosis, the history, the prevalence and much more besides.
THE COMPREHENSIVE GUIDE TO PARKINSON'S DISEASE, which is fully referenced throughout, is by far the most comprehensive and extensive book concerning Parkinson's Disease.
SECTION 1 HISTORY OF PARKINSON'S DISEASE : Chapter 1 (The history of Parkinson's Disease - includes descriptions of it in ancient India, ancient China, the Bible, ancient Greece, ancient Rome, in medieval history, and during the 16th, 17th, 18th and recent centuries), Chapter 2 (Famous people with Parkinson's Disease)
SECTION 2 PREVALENCE OF PARKINSON'S DISEASE : Chapter 3 (Prevalence of Parkinson's Disease - the world's highest prevalence, the world's lowest prevalence, prevalence rates by country, incidence rates by country, age distribution, gender differences, and occupational differences)
SECTION 3 BIOCHEMISTRY OF PARKINSON'S DISEASE : Chapter 4 (Dopamine biosynthesis), Chapter 5 (Coenzyme biosynthesis), Chapter 6 (Iron metabolism), Chapter 7 (Zinc metabolism), Chapter 8 (Manganese metabolism), Chapter 9 (Dopamine receptors), Chapter 10 (G proteins), Chapter 11 (Dopamine receptor phosphoprotein)
SECTION 4 CYTOLOGY OF PARKINSON'S DISEASE : Chapter 12 (Dopaminergic neurons), Chapter 13 (Cytological effects - superoxide anion, neuromelanin formation, iron accumulation, the accumulation of alpha-synuclein, and the formation of Lewy bodies)
SECTION 5 ANATOMY OF PARKINSON'S DISEASE : Chapter 14 (Dopaminergic neuronal groups), Chapter 15 (Anatomical effects - on each system in the body)
SECTION 6 PHYSIOLOGY OF PARKINSON'S DISEASE : Chapter 16 (Dopaminergic pathways), Chapter 17 (Physiological effects - on each system in the body)
SECTION 7 SYMPTOMS OF PARKINSON'S DISEASE (symptoms, prevalence, causes of symptoms) : Chapter 18 (Primary symptoms), Chapter 19 (Symptom progression), Chapter 20 (Muscular system), Chapter 21 (Nervous system), Chapter 22 (Alimentary system), Chapter 23 (Urinary system), Chapter 24 (Cardiovascular system), Chapter 25 (Respiratory system), Chapter 26 (Skeletal system), Chapter 27 (Integumentary system), Chapter 28 (Sensory system), Chapter 29 (Endocrine system), Chapter 30 (Reproductive system), Chapter 31 (Immune system)
SECTION 8 DIAGNOSIS OF PARKINSON'S DISEASE : Chapter 32 (Observational methods), Chapter 33 (Technological methods), Chapter 34 (Chemical methods)
SECTION 9 CAUSES OF PARKINSON'S DISEASE : Chapter 35 (Biochemical causes), Chapter 36 (Toxic causes - the chemistry, common sources, means of toxicity, symptoms of each of the toxic causes), Chapter 37 (Genetic causes - the gene, chromosome, biochemical function, type of inheritance, symptoms, prevalence, genetic tests for each of the 40 known genetic causes), Chapter 38 (Pharmacological causes - their pharmacology, adverse effects, causes of symptoms of all the pharmacological causes), Chapter 39 (Medical causes - the pathophysiology, symptoms, causes of symptoms of all the medical disorders that can cause Parkinson's Disease symptoms)
SECTION 10 TREATMENTS OF PARKINSON'S DISEASE (their pharmacology, biochemistry, efficacy, adverse effects) : Chapter 40 (Biochemical treatment), Chapter 41 (L-dopa), Chapter 42 (Dopamine agonists), Chapter 43 (MAO inhibitors), Chapter 44 (COMT inhibitors), Chapter 45 (Anti-cholinergics), Chapter 46 (Non-dopaminergic), Chapter 47 (Surgical treatments), Chapter 48 (Natural treatments), Chapter 49 (Exercise methods), Chapter 50 (Technological methods)
APPENDIX : Appendix 1 (Parkinson's Disease organisations), Appendix 2 (Parkinson's Disease web sites), Appendix 3 (Parkinson's Disease nursing books)